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Comparative Effectiveness Research Training and Instruction (CERTaIN)

Offered By: The University of Texas MD Anderson Cancer Center via edX

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Health Care Courses Data Analysis Courses Research Methods Courses

Course Description

Overview

Do you want to inform healthcare decisions by conducting research on the effectiveness, benefits, and potential harms of treatment options? Would you like to help patients choose care that best meets their needs? Perhaps you’d like to learn the basics of clinical research? Or maybe you’d like to use a national health data registry to answer a research question? If any of these questions resonate Comparative Effectiveness Research Training and Instruction – CERTaIN - Professional Certificate Program is right for you!

Created by investigators from The University of Texas MD Anderson Cancer Center and partner institutions, the CERTaIN Professional Certificate program provides a comprehensive overview of core concepts, research methods and data analysis techniques used in comparative effectiveness (CER) and patient-centered outcomes research (PCOR) across five key areas:

Course 1. Introduction
Course 2. Knowledge Synthesis
Course 3. Patient-Centered Outcomes Research (PCOR)
Course 4. Pragmatic Clinical Trials and Healthcare Delivery Evaluations
Course 5. Observational Studies and Registries

Learn from expert decision scientists, biostatisticians, oncologists, economists, social scientists, health care policy experts and epidemiologists how to conduct CER/PCOR and see how CER/PCOR methods have been applied in the real world to conduct state of the art research studies.

The CERTaIN Professional Certificate Program is intended for anyone interested in CER/PCOR methods. This program is comprised of 5 courses and includes a combined total of almost 50 lectures in CER/PCOR topics. Each course consists of a series of lectures delivered by content experts and each lecture is segmented into short videos, followed by a quiz to assess your understanding of the material.

The CERTaIN Professional Certificate Program is supported by grant number R25HS023214 from the Agency for Healthcare Research and Quality.

The CERTaIN Professional Certificate Program was created by investigators.


Syllabus

Courses under this program:
Course 1: CERTaIN: CER/PCOR Methods: Introduction

Learn the fundamentals of comparative effectiveness research (CER) and patient-centered outcomes research (PCOR) methods and data analysis strategies.



Course 2: CERTaIN: Knowledge Synthesis: Systematic Reviews and Clinical Decision Making

Learn how to interpret and report systematic review and meta-analysis results, and define strategies for searching and critically appraisingscientific literature.



Course 3: CERTaIN: Patient-Centered Outcomes Research

Learn what comparative effectiveness research (CER) and patient-centered outcomes research (PCOR) are and identify the difference between CER/PCOR studies and randomized controlled trials.



Course 4: CERTaIN: Pragmatic Clinical Trials and Healthcare Delivery Evaluations

Learn the fundamentals of pragmatic clinical trials, including study design and basic analytic methods.



Course 5: CERTaIN: Observational Studies and Registries

Define several types of observational studies, interpret their results, and describe how health registries can be used to make decisions about best clinical care.




Courses

  • 0 reviews

    3 weeks, 1-2 hours a week, 1-2 hours a week

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    In this course, you will be introduced to basic statistics and study designs used in CER/PCOR and the ethical considerations to take into account when conducting CER/PCOR.

    This introductorycourse includes 4 lectures:

    1. Basic Statistics for PCOR/CER I
    2. Basic Statistics for PCOR/CER II
    3. Ethics
    4. Introduction to Comparative Effectiveness and Patient-Centered Outcomes Research

    This course is intended for anyone interested in CER/ PCOR methods.

    This course is supported by grant number R25HS023214 from the Agency for Healthcare Research and Quality.

  • 0 reviews

    3 weeks, 4-5 hours a week, 4-5 hours a week

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    Discover practical ways to critically appraise scientific literature, including the conduction and interpretation of systematic reviews and meta-analyses. Additionally, you will learn how to conduct literature searches using online academic databases, hear about economic evaluations, and understand how clinical practice guidelines are used to guide decision making.

    This course includes the following 11 lectures:

    1. Overview of Systematic Reviews
    2. Finding and Managing the Evidence from the Biomedical Literature
    3. Intervention Reviews Methodology
    4. Meta-Analysis of Clinical Trials: Direct Comparisons
    5. Introduction to Meta-Analysis: Indirect Comparisons
    6. Meta-Analysis of Non-Randomized Studies
    7. Diagnostic Test Evaluation
    8. Meta-Synthesis
    9. Clinical Practice Guidelines
    10. Economic Evaluation
    11. Decision Analysis for Outcomes Research

    This course is intended for anyone interested in comparative effectiveness research (CER) and patient-centered outcomes research (PCOR) methods.

    This course is supported by grant number R25HS023214 from the Agency for Healthcare Research and Quality.

  • 1 review

    3 weeks, 3-4 hours a week, 3-4 hours a week

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    In this course, you will learn about the characteristics of CER/PCOR, compare and contrast CER/PCOR studies and randomized controlled trials, and you will hear how PCOR researchers have overcome a variety of barriers to ensure patient-centered care.

    This course includes the following 11 lectures:

    1. Engaging Patients and Stakeholders in Patient-Centered Outcomes Research
    2. Principles of Community-Based Participatory Research
    3. Shared Decision Making in Cancer: Models and Methods
    4. Patient Decision Support Tools in Cancer
    5. An Overview of Patient-Reported Outcomes in Cancer
    6. Designing Surveys: Asking Questions with a Purpose
    7. Qualitative Methods of Research
    8. Dissemination and Implementation Research in PCOR: Translating Knowledge Into Practice
    9. The Role of Health Literacy in Patient-Centered Outcomes Research
    10. Cognitive Impairment and Participation in Research
    11. Behavioral Interventions in Patient-Centered Outcomes Research

    This course is intended for anyone interested in comparative effectiveness research (CER) and patient-centered outcomes research (PCOR) methods.

    This course is supported by grant number R25HS023214 from the Agency for Healthcare Research and Quality.

  • 0 reviews

    3 weeks, 4-5 hours a week, 4-5 hours a week

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    In this course, experts will discuss the options a researcher must consider when embarking on clinical research. What research design should I choose? How do I start the process of getting my research approved? How will I analyze the data I collect? These are all important questions that a researcher faces.

    We will discuss the key decisions a researcher needs to make when preparing for and conducting research, as well as tools for data analysis. You will learn what a pragmatic clinical trial is and how to calculate power and sample size for your study. You will also be exposed to more complex study designs sometimes used in pragmatic clinical trials, such as Bayesian and adaptive designs.

    This course includes the following 11 lectures:

    1. Overview of Design Options for Pragmatic Clinical Trials
    2. Outcome Measures in Clinical Trials
    3. Non-inferiority Trials
    4. Basic Analytic Methods
    5. Basic Power and Sample Size Calculations
    6. SMART: Adaptive Treatment Strategies
    7. Introduction to Bayesian Methods
    8. Bayesian Designs
    9. Quasi-Experiment in Health Services Research
    10. Adaptive Trial Design
    11. Logistics of Clinical Trials

    This course is intended for anyone interested in comparative effectiveness research (CER) and patient-centered outcomes research (PCOR) methods.

    This course is supported by grant number R25HS023214 from the Agency for Healthcare Research and Quality.

  • 0 reviews

    3 weeks, 4-5 hours a week, 4-5 hours a week

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    While randomized controlled trials are considered to be the "gold standard" in health research, they cannot always be performed, for ethical or practical reasons. Observational studies gather information from data that has already been collected, or by observing and measuring patients' changes in health status and their response to interventions outside of a clinical trial. In this course, you will learn to identify the characteristics of observational studies, to interpret the results of observational studies, and to describe the use of health registries in comparative effectiveness research (CER).

    This course includes the following 11 lectures:

    1. Overview of Using Observational Data in Comparative Effectiveness Research (CER)
    2. Cancer Registries and Data Linkage
    3. SEER-Medicare and Other Data Sources
    4. Overview of Analytic Methods I
    5. Overview of Analytic Methods II
    6. Longitudinal Data Analysis
    7. Advanced Methods in CER I
    8. Advanced Methods in CER II
    9. Survival Analysis
    10. Analysis of Medical Cost Data in Observational Studies
    11. Healthcare Policy Research

    This course is intended for anyone interested in comparative effectiveness research (CER) and patient-centered outcomes research (PCOR) methods.

    This course is supported by grant number R25HS023214 from the Agency for Healthcare Research and Quality.


Taught by

Barry R. Davis, MD, PhD, Maria E. Suarez-Almazor, MD, PhD, Maria A. Lopez-Olivo, MD, PhD, Robert J. Volk, PhD and Sharon H. Giordano, MD, MPH, FASCO

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