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Dynamical Modeling Methods for Systems Biology

Offered By: Icahn School of Medicine at Mount Sinai via Coursera

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Biology Courses MATLAB Courses Systems Biology Courses Partial Differential Equations Courses Ordinary Differential Equations Courses

Course Description

Overview

An introduction to dynamical modeling techniques used in contemporary Systems Biology research. We take a case-based approach to teach contemporary mathematical modeling techniques. The course is appropriate for advanced undergraduates and beginning graduate students. Lectures provide biological background and describe the development of both classical mathematical models and more recent representations of biological processes. The course will be useful for students who plan to use experimental techniques as their approach in the laboratory and employ computational modeling as a tool to draw deeper understanding of experiments. The course should also be valuable as an introductory overview for students planning to conduct original research in modeling biological systems. This course focuses on dynamical modeling techniques used in Systems Biology research. These techniques are based on biological mechanisms, and simulations with these models generate predictions that can subsequently be tested experimentally. These testable predictions frequently provide novel insight into biological processes. The approaches taught here can be grouped into the following categories: 1) ordinary differential equation-based models, 2) partial differential equation-based models, and 3) stochastic models.

Syllabus

  • Introduction | Computing with MATLAB
    • The description goes here
  • Introduction to Dynamical Systems
    • The description goes here
  • Bistability in Biochemical Signaling Models
    • The description goes here
  • Computational Modeling of the Cell Cycle
    • The description goes here
  • Modeling Electrical Signaling
    • The description goes here
  • Modeling with Partial Differential Equations
    • The description goes here
  • Stochastic Modeling
    • The description goes here

Taught by

Eric Sobie

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