Clinical Pharmacokinetics: Dosing and Monitoring

Explore the key principles of pharmacokinetics and how to apply them

On this course you will learn about the principles of clinical pharmacokinetics, including factors that affect the absorption, distribution, metabolism, excretion, and binding of drugs. You will learn how to integrate these principles into the process of monitoring, evaluating and adjusting dosing for patients.

You will learn through critical thinking and problem-solving exercises that relate to drug dosing and monitoring functions, that are commonly performed by pharmacists in clinical practice.

This course is for professionals or students looking to build their clinical pharmacokinetic knowledge. You might be an undergraduate pharmacy student, a postgraduate pharmacy student or a pharmacist in clinical practice.

• The Fish Tank – A Simplified Model of First-Order Elimination
• Welcome to this course
• The Fish Tank Model - Introduction and Definition
• Assessment of the week
• Dosing Basics – How to Determine the Right Amount of Drug for a Patient
• How to Determine the Right Amount of Drug for a Patient
• The Ups and Downs of Predicting Changes in Drug Concentration
• Predicting changes in drug concentration
• The Challenges of Assessing Renal and Hepatic Clearance
• Renal and hepatic dose adjustment
• What Pharmacists Need to Know about Dosing Aminoglycosides and Vancomycin
• How to optimize efficacy and minimize toxicity on dosing Vancomycin and Aminoglycoside?
• Clinical Application - Vancomycin and Gentamycin Case Practice
• Clinical recommendations on the dose adjustment on Vancomycin and Aminoglycoside
• Assessment of the Course