Bacterial Genomes I: From DNA to Protein Function Using Bioinformatics

Join us in our quest to discover what makes microbes dangerous. Use bioinformatics to probe genomes, to explore and represent DNA and protein sequences. Then, use databases to find protein sequences’ conserved domains and investigate their functions.

The course will be of interest to undergraduates, post-graduates, researchers, bioinformaticians, biomedical researchers, microbiologists, healthcare professionals and all those who are interested in learning about the underlying mechanisms of bacterial disease, DNA sequences and protein data, or how to use online analytical tools to probe genomes.

The topics covered in this course are applicable to the genomes of all organisms. It is not essential to have previous knowledge or experience in bioinformatics. Scientific terminology is explained. The opportunity to use online computational tools in the context of bacterial genomes will also be of interest to teachers and their 16-18-year-old science and computing students.

No specific software, hardware, or other resources are required.

• Introduction to DNA and protein sequences
• Welcome to the Course
• Gene and Protein sequences
• Primary databases
• End of Week 1
• From Sequence to Function
• Homology searches
• Biological databases
• From sequence to function
• Concluding discussion, reflection with next steps, and acknowledgments